Microneedling with Exosomes: What You Need to Know

Microneedling with Exosomes: What You Need to Know

Are you seeking a revolutionary approach to rejuvenate skin and address challenges like acne scarring? Microneedling with exosomes might be the answer. This innovative treatment combines the rejuvenating power of exosomes with the effectiveness of microneedling, offering long-lasting and significant improvements in skin quality.

Exosome Therapy: Regenerative Power of Now

What are exosomes?

Exosomes are tiny extracellular vesicles rich in growth factors, cytokines, and nucleic acids, which aid in skin healing and regeneration.


How are exosomes derived?

The process starts with harvesting exosomes from mesenchymal stem cells. These exosomes are then concentrated and integrated into a serum, which can be applied to the skin in clinic during microneedling and used at home for optimal results.


What is exosome therapy?

There are several methods of exosome therapy in aesthetics, namely involving topical application of exosomes. Microneedling is one of the most effective as it allows the exosomes to penetrate deeper and stimulate cellular renewal on multiple layers of tissue, making them more efficient than solely topical application.

Understanding the Benefits of Exosomes for Skin Health

Exosomes offer a variety of benefits for skin health:

  • Collagen Production: They activate fibroblasts to boost collagen, enhancing skin elasticity and reducing fine lines.
  • Cellular Regeneration: Exosomes carry growth factors that promote the development of new skin cells, aiding in tissue repair.
  • Wound Healing: Their anti-inflammatory properties accelerate the healing of wounds and scars.
  • Skin Hydration: They contain lipids and proteins that improve skin moisture levels.
  • Pigmentation Control: Exosomes help regulate melanin production, aiding in reducing hyperpigmentation and evening out skin tone.

Microneedling with Exosomes: Harnessing Biostimulation and Regeneration for Enhanced Skin Rejuvenation

Microneedling, a treatment known for its ability to stimulate the skin’s natural healing response, creates fine micro-channels across the skin’s surface. This biostimulatory treatment not only promotes collagen induction but also prepares the skin to more effectively absorb the exosome serum.

When these two powerful modalities are combined, the effects are synergistic. The exosomes, packed with growth factors, cytokines, and regenerative molecules, penetrate deeply into the skin via the channels created by microneedling. This results in a more efficient delivery system, directly targeting the skin’s deeper layers where cellular renewal and repair processes occur.

Did you know? Dp Dermaceuticals professional exosome serum, MG-EXO-SKIN, contains patented HylaFuse technology that further optimizes delivery deep into layers of tissue. 


The impact of this combination is multi-faceted. Collagen production, a critical component of skin elasticity and youthfulness, is significantly boosted, leading to a reduction in fine lines and wrinkles. The healing properties of exosomes further accelerate the repair of skin tissues, enhancing the overall texture and tone of the skin. This dual action not only speeds up the skin's natural rejuvenation process but also amplifies it, leading to more pronounced and long-lasting results.

In essence, microneedling with exosomes is a holistic approach to skin health that leverages the body's own regenerative capabilities for truly transformative outcomes.

Exosome Therapy FAQs

  1. How does it work? Exosome therapy uses vesicles from stem cells containing growth factors and genetic material to promote skin regeneration.
  2. What concerns does it address? It's effective for skin rejuvenation, scar revision, and hair loss, to name a few.
  3. Side effects or risks? It's generally safe with minimal side effects.
  4. Comparison with stem cell therapy? Exosomes are not cells and do not have a nucleus, but they offer similar regenerative properties without the complexity and ethical concerns associated with live stem cells.


Best Exosome Serums

Best Exosome Serum for Home Use

  • Dp Dermaceuticals EXO-SKIN: One of the only exosome serums suitable for daily use, it is also one of the only shelf-stable exosome products available that does not require refrigeration!

Best Exosome Serum for Professional Use

  • Dp Dermaceuticals MG-EXO-SKIN Professional Microneedling Serum: This serum specifically designed for use with microneedling is only available to authorized Dp Derm providers. Not registered? Apply here now. MG-EXO-Skin enhances natural cellular repair for younger-looking skin. Its regenerative capabilities accelerate microneedling results, helping improve various skin concerns such as sun damage, aging, rosacea, and pigmentation. It features a dual delivery system with the HylaFuse Complex and Calphasomes for optimal results. 


Are you a professional microneedling treatment provider? Find out how the Dp4 Microneedling System can revolutionize your practice. 


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